V-LABS/6-乙酰氨基-6-脱氧司他丁精胺/1 mg/IS0239
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3392242852
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4000-520-616
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商品介绍
6-Acetomido-6-deoxycastanospermine
Product Code: IS0239
Total:£0.00
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Product Description
| Chemical | |
| Description | A powerful inhibitor of hexosaminidases. Inhibits β-N-acetylglucosaminidases, enzymes which catalyse the hydrolysis of β-N-acetylglucosamine residues of lipid or protein-linked oligosaccharides, these are potentially useful targets for cancer chemotherapy. β-N-acetylglucosaminidases may be associated with the invasiveness of certain tumours and high activity levels of these enzymes have been found in serum and urine of patients with various malignancies. 6-Acetamido-6-deoxycastanospermine was tested against a panel of glycosidases and was found to be a very potent inhibitor of β-N-acetylglucosaminidases from human placenta (IC50 = 0.5 mM), bovine kidney (IC50 = 1.5 mM), jack bean (IC50 = 1.6 m M), porcine placenta (IC50 = 0.4 mM) and bovine epididymis (IC50 = 0.7 mM). Reference:Tett. Lett. 32, 6, 719-720. |
| CAS Number | 134100-29-1 |
| Formula | C10H18N2O4 |
| Molecular Weight | 230.26 |
| Alternative Name(s) | CastNAc |
品牌介绍
Dextra was founded in 1989 in Reading (UK) to provide carbohydrate synthesis and analytical services to the scientific research community. Since then, the company has gained a world-wide reputation for the supply of rare sugars, oligosaccharides and chiral molecules for medical research, diagnostics and pharmaceutical applications. Dextra has successfully achieved ISO9001:2008 registration for its activities.
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